Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.43 |
| ▸ | CD69 | Q07108 | 2/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.42 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
| ▸ | PYGB | P11216 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888480 | 1.00 | MAPK1 (0.66) | MAPK1ALDH1A1THRBNOD2KDM4E | |
| SCHEMBL11425414 | 1.00 | MAPK1 (0.66) | MAPK1ALDH1A1THRBNOD2KDM4E | |
| SCHEMBL8000040 | 1.00 | MAPK1 (0.66) | MAPK1ALDH1A1THRBNOD2KDM4E | |
| SCHEMBL8000037 | 1.00 | MAPK1 (0.66) | MAPK1ALDH1A1THRBNOD2KDM4E | |
| SCHEMBL23031946 | 0.90 | MAPK1 (0.56) | MAPK1ALDH1A1THRBNOD2KDM4E | |
| SCHEMBL30644644 | 0.90 | MAPK1 (0.56) | MAPK1ALDH1A1THRBNOD2KDM4E | |
| SCHEMBL18984599 | 0.88 | MAPK1 (0.55) | MAPK1ALDH1A1THRBNOD2KDM4E | |
| SCHEMBL8027243 | 0.87 | ALDH1A1 (0.52) | MAPK1ALDH1A1THRBLMNALGALS3 | |
| SCHEMBL7154639 | 0.87 | ALDH1A1 (0.52) | MAPK1ALDH1A1THRBLMNALGALS3 | |
| SCHEMBL7154645 | 0.87 | ALDH1A1 (0.52) | MAPK1ALDH1A1THRBLMNALGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6168934-B1 | EFFICIENT GLYCOSYLATION BY MIXING ACCEPTOR SACCHARIDE, DONOR MONOSACCHARIDE, ACTIVATING NUCLEOTIDE, ACTIVATED DONOR MONOSACCHARIDE REGENERATING SYSTEM, PYROPHOSPHATE SCAVENGER, AND GLYCOSYLTRANSFERASE IN AN AQUEOUS MEDIUM | THE SCRIPPS RESEARCH INSTITUTE | 2001-01-02 | — | — | US | disclosed |
| EP-0576592-B1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | SCRIPPS RESEARCH INST (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5759823-A | MIXING IN AQUEOUS MEDIUM ACTIVATED DONOR MONOSACCHARIDE WITH ACCEPTOR SACCHARIDE IN PRESENCE OF GLYCOSYLTRANSFERASE, MAINTAINING TO GLYCOSYLATE ACCEPTOR SACCHARIDE | SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-02 | — | — | US | disclosed |
| US-5593887-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-01-14 | — | — | US | disclosed |
| US-5461143-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0576592-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016640-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-10-01 | — | — | WO | disclosed |
| US-4238473-A | LOWER CARBOHYDRATES HAVING A BRIDGING ARM GLYCOSIDICALLY LINKED TO AN ALDOSE MOIETY | CHEMBIOMED LIMITED (CA) | 1980-12-09 | — | — | US | disclosed |
| US-4137401-A | Glycoside-ether-ester compounds | CHEMBIOMED LIMITED (CA) | 1979-01-30 | — | — | US | disclosed |