Clioquinol

Clioquinol

SCHEMBL18985133

Oc1c(I)cc(Cl)c2cccnc12.[Cu]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.97
LMNA P02545 5/20 0.97
MEN1 O00255 5/20 0.97
HTT P42858 5/20 0.97
KMT2A Q03164 5/20 0.97
SMN1; SMN2 Q16637 5/20 0.97
TDP1 Q9NUW8 5/20 0.97
HSP90AA1 P07900 5/20 0.97
MAPT P10636 5/20 0.97
METAP2 P50579 5/20 0.97
ALDH1A1 P00352 4/20 0.97
TP53 P04637 3/20 0.97
ALOX15 P16050 3/20 0.97
SLC6A2 P23975 3/20 0.97
MMP14 P50281 3/20 0.97
OPRK1 P41145 3/20 0.97
ALOX12 P18054 3/20 0.97
USP2 O75604 2/20 0.97
CYP3A4 P08684 2/20 0.97
HPGD P15428 2/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clioquinol SCHEMBL11749381 0.98 KDM4E (1.00) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL30592904 0.98 KDM4E (1.00) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL29370380 0.98 KDM4E (1.00) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL3967 0.98 KDM4E (1.00) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL28198183 0.97 KDM4E (0.97) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL27671588 0.97 KDM4E (0.97) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL28524321 0.97 KDM4E (0.97) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL28531298 0.97 KDM4E (0.97) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL28529781 0.97 KDM4E (0.97) KDM4ELMNAMEN1HTTKMT2A
Clioquinol SCHEMBL9339556 0.97 KDM4E (0.97) KDM4ELMNAMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230087131-A1 LIQUID DRESSING COMPOSITIONS AND THEIR VETERINARY USES CAMBRIDGE ENTERPRISE LIMITED (GB) 2023-03-23 US disclosed
EP-4009988-A1 LIQUID DRESSING COMPOSITIONS AND THEIR VETERINARY USES Cambridge Enterprise Limited (GB) 2022-06-15 EP disclosed
EP-4009987-A1 LIQUID DRESSING COMPOSITIONS AND THEIR USES Cambridge Enterprise Limited (GB) 2022-06-15 EP disclosed
CN-114514042-A Liquid dressing composition and veterinary use thereof 剑桥有限公司 2022-05-17 CN disclosed
WO-2021023886-A1 LIQUID DRESSING COMPOSITIONS AND THEIR VETERINARY USES CAMBRIDGE ENTERPRISE LIMITED (GB) 2021-02-11 WO disclosed
WO-2021023885-A1 LIQUID DRESSING COMPOSITIONS AND THEIR USES CAMBRIDGE ENTERPRISE LIMITED (GB) 2021-02-11 WO disclosed
US-20180369143-A1 METAL COMPLEXED THERAPEUTIC AGENTS AND LIPID-BASED NANOPARTICULATE FORMULATIONS THEREOF BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) 2018-12-27 US disclosed
CN-108883117-A Metal complexed therapeutic agents and lipid based nanoparticle formulations thereof 英属哥伦比亚癌症研究分支机构 2018-11-23 CN disclosed
EP-3389665-A1 METAL COMPLEXED THERAPEUTIC AGENTS AND LIPID-BASED NANOPARTICULATE FORMULATIONS THEREOF British Columbia Cancer Agency Branch (CA) 2018-10-24 EP disclosed
WO-2017100925-A1 METAL COMPLEXED THERAPEUTIC AGENTS AND LIPID-BASED NANOPARTICULATE FORMULATIONS THEREOF BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180369143-A1 METAL COMPLEXED THERAPEUTIC AGENTS AND LIPID-BASED NANOPARTICULATE FORMULATIONS THEREOF LIPA, SLC40A1, SLC30A6 KDM4E 4138/4885LMNA 1631/4885MEN1 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.