Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679861 | 0.83 | NPC1 (0.61) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL29783189 | 0.82 | PPARG (0.42) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL18985175 | 0.82 | PPARG (0.42) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL29783272 | 0.81 | NR1H4 (0.47) | LMNAMAPTKMT2AGAANR1H4 | |
| SCHEMBL18985158 | 0.81 | NR1H4 (0.47) | LMNAMAPTKMT2AGAANR1H4 | |
| SCHEMBL18985174 | 0.80 | KDM4E (0.41) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL19027823 | 0.80 | MAPT (0.62) | NPC1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL18985161 | 0.78 | KDM4E (0.39) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12794264 | 0.77 | NPC1 (0.45) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL18985168 | 0.77 | TP53 (0.63) | GAAPOLBTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368425-B | Liquid crystal mixture and liquid crystal display | 默克专利股份有限公司（DE） | 2023-01-13 | — | — | CN | disclosed |
| CN-114702965-A | Liquid crystal mixture and liquid crystal display | 默克专利股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| US-20220106525-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2022-04-07 | — | — | US | disclosed |
| EP-3864111-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-11053442-B2 | Liquid crystal mixture and liquid crystal display | MERCK PATENT GMBH (DE) | 2021-07-06 | — | — | US | disclosed |
| US-11053442-B2 | Liquid crystal mixture and liquid crystal display | MERCK PATENT GMBH (DE) | 2021-07-06 | — | — | US | disclosed |
| CN-112805353-A | Liquid crystal mixture and liquid crystal display | 默克专利股份有限公司 | 2021-05-14 | — | — | CN | disclosed |
| US-20200255740-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2020-08-13 | — | — | US | disclosed |
| US-20200255740-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2020-08-13 | — | — | US | disclosed |
| EP-3390570-B1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3390570-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102068-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102068-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106525-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | CXCR1, PYM1, F11 | LMNA 1207/4885NPC1 345/4885NFKB1 2084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.