Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003259 | 0.84 | MEN1 (0.52) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003458 | 0.81 | MAPT (0.65) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17434438 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL17434434 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL19003459 | 0.76 | CXCR1 (0.51) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17996441 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5595104 | 0.71 | CXCR1 (0.80) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003256 | 0.70 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5595137 | 0.69 | CXCR1 (0.76) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5594608 | 0.69 | CXCR2 (0.76) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | claimed |
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |