Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 2/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003468 | 0.86 | ALDH1A1 (0.62) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18985221 | 0.84 | MEN1 (0.57) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18985254 | 0.84 | MEN1 (0.57) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19003458 | 0.84 | MAPT (0.65) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL19003259 | 0.83 | MEN1 (0.52) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL18985232 | 0.76 | ALDH1A1 (0.54) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL17434434 | 0.76 | ALDH1A1 (0.68) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL17434438 | 0.76 | ALDH1A1 (0.68) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL19003469 | 0.73 | EGFR (0.49) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19003298 | 0.73 | EGFR (0.49) | MAPTSMN1; SMN2ALDH1A1TRPM2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |