Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 4/20 | 0.30 |
| ▸ | LAP3 | P28838 | 3/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528026 | 0.81 | FOLH1 (0.40) | FDPS | |
| SCHEMBL22701 | 0.72 | FDPS (0.34) | FDPSGRM3LAP3 | |
| SCHEMBL6237312 | 0.71 | GCLC (0.33) | FDPSGRM3 | |
| SCHEMBL11338517 | 0.71 | FDPS (0.33) | FDPSGRM3 | |
| SCHEMBL2990247 | 0.69 | MMP1 (0.34) | FDPSMMP1MMP8LAP3 | |
| SCHEMBL6824797 | 0.69 | GRM3 (0.37) | GRM3 | |
| SCHEMBL9787461 | 0.69 | FDPS (0.41) | FDPSMMP1MMP8ANPEPLAP3 | |
| SCHEMBL11434130 | 0.67 | FDPS (0.44) | FDPSMMP1MMP8ANPEPLAP3 | |
| SCHEMBL19211979 | 0.67 | FDPS (0.44) | FDPSMMP1MMP8ANPEPLAP3 | |
| SCHEMBL11334476 | 0.67 | GRM4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100849-A1 | 6-OXOPURINE PHOSPHORIBOSYL TRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-06-22 | — | — | WO | disclosed |