Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.62 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985301 | 1.00 | RAB9A (0.74) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27731432 | 0.87 | ALDH1A1 (0.62) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27752058 | 0.86 | RAB9A (0.67) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27752021 | 0.86 | RAB9A (0.67) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3040771 | 0.86 | RAB9A (0.69) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27752045 | 0.86 | RAB9A (0.67) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3040770 | 0.86 | RAB9A (0.69) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28774771 | 0.83 | MAPT (0.72) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27752016 | 0.83 | RAB9A (0.66) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27752050 | 0.83 | RAB9A (1.00) | RAB9AALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |