Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897013 | 0.86 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DPTPN5 | |
| SCHEMBL1759085 | 0.77 | HTR7 (0.54) | PTPN5 | |
| SCHEMBL1642837 | 0.75 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DCA2 | |
| SCHEMBL11293298 | 0.75 | PDCD1 (0.59) | PDE4BPDE4APDE4CPDE4DCD274 | |
| SCHEMBL2914433 | 0.75 | CA2 (0.61) | PDE4BPDE4APDE4CPDE4DCA2 | |
| SCHEMBL30288300 | 0.75 | CA2 (0.61) | PDE4BPDE4APDE4CPDE4DCA2 | |
| SCHEMBL34462740 | 0.74 | TAAR1 (0.51) | CD274PDCD1 | |
| SCHEMBL1642694 | 0.73 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DCA2 | |
| SCHEMBL29065608 | 0.73 | CA2 (0.59) | PDE4BPDE4APDE4CPDE4DCA2 | |
| SCHEMBL3809080 | 0.73 | CA2 (0.59) | CA2ATMGABRA1GABRB2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493934-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056428-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |