Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985804 | 0.74 | LRRK2 (0.47) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL28174563 | 0.69 | MAPT (0.47) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL17688945 | 0.66 | TLR8 (0.45) | JMJD6ADRA1AKDM4EMAPTKMT2A | |
| SCHEMBL15096492 | 0.65 | JMJD6 (0.39) | JMJD6ADRA1AALDH1A1MAPTKMT2A | |
| SCHEMBL24027041 | 0.65 | ACSS2 (0.40) | JMJD6ADRA1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL16823798 | 0.65 | HTT (0.43) | JMJD6ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL31306191 | 0.64 | KEAP1 (0.61) | JMJD6ADRA1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL18985809 | 0.63 | AAK1 (0.38) | KDM4EMAPT | |
| SCHEMBL27571353 | 0.63 | MAPT (0.52) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL28964159 | 0.63 | KMT2A (0.47) | JMJD6ADRA1AKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390387-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |