Fluoride Ion

Fluoride Ion

SCHEMBL1898574

CCCn1cc[n+](C)c1.[F-]

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.66
MEN1 O00255 2/20 0.66
HSP90AA1 P07900 2/20 0.66
KMT2A Q03164 2/20 0.66
APAF1 O14727 1/20 0.66
NPC1 O15118 1/20 0.66
PLA2G1B P04054 1/20 0.66
MAPT P10636 1/20 0.66
MAPK1 P28482 1/20 0.66
HTT P42858 1/20 0.66
RAB9A P51151 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
ATG4B Q9Y4P1 1/20 0.66
FDPS P14324 5/20 0.39
LMNA P02545 1/20 0.37
PON1 P27169 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293656 0.98
SCHEMBL17139699 0.98 SMN1; SMN2 (0.68) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Iodide SCHEMBL180142 0.95 SMN1; SMN2 (0.66) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Iodide SCHEMBL3774573 0.95 SMN1; SMN2 (0.66) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Fluoride SCHEMBL28444338 0.95 SMN1; SMN2 (0.66) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Bromide SCHEMBL557293 0.95 SMN1; SMN2 (0.71) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Hydrochloric Acid SCHEMBL556929 0.95 SMN1; SMN2 (0.66) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Water SCHEMBL28929074 0.95 SMN1; SMN2 (0.66) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL25362454 0.90 SMN1; SMN2 (0.59) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL1681979 0.90 SMN1; SMN2 (0.59) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1698606-B1 FLUORINATING AGENT AND METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND USING SAME SUMITOMO CHEMICAL CO (JP) 2013-02-20 EP disclosed
US-7939697-B2 Fluorinating agent and method for producing fluorine-containing compound using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-10 US disclosed
US-20090287025-A1 Fluorinating agent and method for producing fluorine-containing compound using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2009-11-19 US disclosed
US-7569703-B2 Fluorinating agent and method for producing fluorine-containing compound using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-04 US disclosed
US-20070135634-A1 Fluorinating agent and method for producing fluorine-containing compound using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-06-14 US disclosed
EP-1698606-A1 FLUORINATING AGENT AND METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND USING SAME Sumitomo Chemical Company, Limited (JP) 2006-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135634-A1 Fluorinating agent and method for producing fluorine-containing compound using the same AFF1, AFF2, AFF4 SMN1; SMN2 1227/4885MEN1 86/4885HSP90AA1 4216/4885
US-20090287025-A1 Fluorinating agent and method for producing fluorine-containing compound using the same AFF1, AFF2, AFF4 SMN1; SMN2 1227/4885MEN1 86/4885HSP90AA1 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.