Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | APAF1 | O14727 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.66 |
| ▸ | FDPS | P14324 | 5/20 | 0.39 |
| ▸ | PON1 | P27169 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17139699 | 0.98 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL293656 | 0.98 | — | — | |
| Iodide SCHEMBL180142 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Fluoride Ion SCHEMBL1898574 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Bromide SCHEMBL557293 | 0.95 | SMN1; SMN2 (0.71) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Fluoride SCHEMBL28444338 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Water SCHEMBL28929074 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Iodide SCHEMBL3774573 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Hydrochloric Acid SCHEMBL8018852 | 0.92 | MEN1 (0.73) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL25362454 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | JIANGSU CELLURANICS NEW MATERIAL TECHNOLOGY CO., LTD. (CN) | 2025-06-12 | — | — | US | claimed |
| CN-119350702-A | Preparation method of spectrum-adjustable flexible cellulose-based aerogel material | 南京工业大学 | 2025-01-24 | — | — | CN | claimed |
| EP-4477651-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | Jiangsu Celluranics New Material Technology Co., Ltd. (CN) | 2024-12-18 | — | — | EP | claimed |
| CN-119049824-A | Magnetorheological shear thickening fluid with flame retardant and anti-sedimentation effects and preparation method thereof | 中国科学技术大学 | 2024-11-29 | — | — | CN | claimed |
| CN-112624131-B | Preparation method of monodisperse large-particle-size silicon dioxide microspheres | 深圳先进电子材料国际创新研究院 | 2022-09-06 | — | — | CN | claimed |
| CN-112791010-B | Chestnut shell aerogel and preparation method and application thereof | 华南理工大学 | 2022-05-24 | — | — | CN | claimed |
| CN-114420896-A | High-rate lithium battery negative electrode piece and preparation method and application thereof | 中国科学院上海硅酸盐研究所 | 2022-04-29 | — | — | CN | claimed |
| CN-109651114-B | Method for synthesizing alkyl aromatic aldehyde | 中国石油化工股份有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109647528-B | Catalyst for synthesizing alkyl aromatic aldehyde | 中国石油化工股份有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109651112-B | Method for synthesizing alkyl aromatic aldehyde by alkyl aromatic hydrocarbon carbonylation | 中国石油化工股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| US-20050205493-A1 | Ionic liquids as solvents in headspace gas chromatography | NOVARTIS AG (CH) | 2005-09-22 | — | — | US | claimed |
| EP-1311472-B1 | METHOD FOR PREPARING ALKOXYAMINES FROM NITROXIDES | ATOFINA (FR) | 2004-10-20 | — | — | EP | claimed |
| US-6700007-B2 | IN A BIPHASIC MEDIUM, BY MIXING AN IONIC LIQUID SUCH AS AN ALKYLIMIDAZOLIUM HALIDE, AN ORGANIC SOLVENT, A TRANSITION METAL SALT, A METAL LIGAND, A HALOHYDROCARBON AND A NITROXIDE | ATOFINA (FR) | 2004-03-02 | — | — | US | claimed |
| US-6579343-B2 | Contacting gas with a liquid ionic compound comprising a nitrogen-containing heterocyclic cation | UNIVERSITY OF NOTRE DAME DU LAC | 2003-06-17 | — | — | US | claimed |
| US-20030050507-A1 | Method for prepararing alkoxyamines from nitroxides | ATOFINA (FR) | 2003-03-13 | — | — | US | claimed |
| US-20020189444-A1 | Purification of gas with liquid ionic compounds | NATIONAL SCIENCE FOUNDATION | 2002-12-19 | — | — | US | claimed |
| WO-2000040673-A1 | INDUSTRIAL PROCESS AND CATALYSTS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-07-13 | — | — | WO | claimed |
| US-5994602-A | IN THE PRESENCE OF A HYDROCARBYL ALUMINUM OR GALLIUM HALIDE AND A HYDROCARBYL-SUBSTITUTED IMIDAZOLIUM OR PYRIDINIUM HALIDE | BP CHEMICALS LIMITED (GB) | 1999-11-30 | — | — | US | claimed |
| EP-0693045-B1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1997-10-22 | — | — | EP | claimed |
| EP-0791643-A1 | Lubricating oils | BP Chemicals Limited (GB) | 1997-08-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050507-A1 | Method for prepararing alkoxyamines from nitroxides | ZYX, ZFX, PNMT | SMN1; SMN2 3622/4885MEN1 4242/4885HSP90AA1 4154/4885 |
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | HPD, DPYD, PGD | SMN1; SMN2 4474/4885MEN1 4667/4885HSP90AA1 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.