Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | APAF1 | O14727 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 5/20 | 0.39 |
| ▸ | PON1 | P27169 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293656 | 0.98 | — | — | |
| SCHEMBL17139699 | 0.98 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Iodide SCHEMBL180142 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Water SCHEMBL28929074 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Hydrochloric Acid SCHEMBL556929 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Fluoride Ion SCHEMBL1898574 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Iodide SCHEMBL3774573 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Fluoride SCHEMBL28444338 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL25362454 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL15732335 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | JIANGSU CELLURANICS NEW MATERIAL TECHNOLOGY CO., LTD. (CN) | 2025-06-12 | — | — | US | claimed |
| CN-119181850-A | Electrolyte for improving performance of zinc-halogen battery and preparation method thereof | 广东工业大学 | 2024-12-24 | — | — | CN | claimed |
| EP-4477651-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | Jiangsu Celluranics New Material Technology Co., Ltd. (CN) | 2024-12-18 | — | — | EP | claimed |
| CN-118738599-A | Electrolyte of local high-concentration ionic liquid, preparation method of electrolyte and assembled zinc tellurium battery with high voltage | 广东工业大学 | 2024-10-01 | — | — | CN | claimed |
| CN-116477576-A | Application of amino acid functional ionic liquid in iodine extraction | 辽宁大学 | 2023-07-25 | — | — | CN | claimed |
| CN-115732749-A | Composite solid electrolyte and preparation method thereof | 多氟多新材料股份有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-115141410-A | Porous polymer pressure-sensitive film, preparation method and application thereof | 江苏烨湫传感科技有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-113403636-B | Synthetic method of alpha, beta-dichlorobenzene sulfoxide compound | 新疆大学 | 2022-09-13 | — | — | CN | claimed |
| CN-114420896-A | High-rate lithium battery negative electrode piece and preparation method and application thereof | 中国科学院上海硅酸盐研究所 | 2022-04-29 | — | — | CN | claimed |
| CN-109651114-B | Method for synthesizing alkyl aromatic aldehyde | 中国石油化工股份有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-112830907-B | Method for preparing 5-hydroxymethylfurfural | 中国科学院宁波材料技术与工程研究所 | 2022-03-22 | — | — | CN | claimed |
| CN-113308109-A | Flexible perovskite quantum dot polymer film and preparation method and application thereof | 江苏烨湫传感科技有限公司 | 2021-08-27 | — | — | CN | claimed |
| CN-112830907-A | Method for preparing 5-hydroxymethylfurfural | 中国科学院宁波材料技术与工程研究所 | 2021-05-25 | — | — | CN | claimed |
| CN-110092907-B | Thioether-containing high-temperature-resistant shape memory polyamide resin and preparation method and application thereof | 四川大学 | 2020-05-26 | — | — | CN | claimed |
| CN-110819278-A | Novel double-component AB adhesive and preparation and use methods thereof | 江苏大力士投资有限公司 | 2020-02-21 | — | — | CN | claimed |
| EP-2543755-B1 | CELLULOSE NANOFIBERS, METHOD FOR PRODUCING SAME, COMPOSITE RESIN COMPOSITION AND MOLDED BODY | OLYMPUS CORP (JP) | 2018-02-14 | — | — | EP | claimed |
| EP-1311472-B1 | METHOD FOR PREPARING ALKOXYAMINES FROM NITROXIDES | ATOFINA (FR) | 2004-10-20 | — | — | EP | claimed |
| US-6700007-B2 | IN A BIPHASIC MEDIUM, BY MIXING AN IONIC LIQUID SUCH AS AN ALKYLIMIDAZOLIUM HALIDE, AN ORGANIC SOLVENT, A TRANSITION METAL SALT, A METAL LIGAND, A HALOHYDROCARBON AND A NITROXIDE | ATOFINA (FR) | 2004-03-02 | — | — | US | claimed |
| WO-2003051894-A1 | PREPARATION OF IONIC LIQUIDS | CYTEC CANADA INC. (CA) | 2003-06-26 | — | — | WO | claimed |
| US-20030050507-A1 | Method for prepararing alkoxyamines from nitroxides | ATOFINA (FR) | 2003-03-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050507-A1 | Method for prepararing alkoxyamines from nitroxides | ZYX, ZFX, PNMT | SMN1; SMN2 3622/4885MEN1 4242/4885HSP90AA1 4154/4885 |
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | HPD, DPYD, PGD | SMN1; SMN2 4474/4885MEN1 4667/4885HSP90AA1 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.