Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606375 | 0.98 | CYP1A2 (0.38) | CYP1A2CYP3A4LMNACYP2D6CYP2C9 | |
| SCHEMBL18981 | 0.83 | TNF (0.36) | CYP1A2CYP3A4LMNACYP2D6CYP2C9 | |
| SCHEMBL17511900 | 0.79 | CLK1 (0.40) | CYP1A2CYP3A4LMNACYP2D6CYP2C9 | |
| SCHEMBL17511944 | 0.79 | CLK1 (0.40) | CYP1A2CYP3A4LMNACYP2D6CYP2C9 | |
| SCHEMBL17511936 | 0.75 | KDM4E (0.42) | CYP1A2CYP3A4LMNACYP2D6CYP2C9 | |
| SCHEMBL81524 | 0.73 | — | — | |
| SCHEMBL275946 | 0.73 | LMNA (0.33) | CYP1A2CYP3A4LMNACYP2D6CYP2C9 | |
| Pyridine SCHEMBL28171568 | 0.72 | TSHR (0.38) | KDM4E | |
| SCHEMBL17511941 | 0.72 | KDM4E (0.47) | CYP1A2CYP3A4LMNACYP2D6CYP2C9 | |
| SCHEMBL199205 | 0.72 | SIGMAR1 (0.36) | CYP1A2CYP3A4LMNASIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 18204 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392032-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR FOR THE TREATMENT OR PREVENTION OF RENAL CYSTIC DISEASE AND CARDIORENAL SYNDROME | Arena Pharmaceuticals, Inc. (US) | 2024-07-03 | — | — | EP | claimed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | claimed |
| EP-4361141-A1 | PROTEIN DEGRADATION AGENT | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2024-05-01 | — | — | EP | claimed |
| US-20240124453-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2024-04-18 | — | — | US | claimed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117813306-A | Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use | 上海科州药物研发有限公司 | 2024-04-02 | — | — | CN | claimed |
| US-20240101546-A1 | HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | EUBULUS BIOTHERAPEUTICS INC (CN) | 2024-03-28 | — | — | US | claimed |
| WO-2024040497-A1 | ANTIVIRAL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-02-29 | — | — | WO | claimed |
| CN-117545749-A | Protein degradation agent | 苏州开拓药业股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| WO-2024027694-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2024-02-08 | — | — | WO | claimed |
| EP-0463444-A1 | Dicarboxylic acid imides as herbicides | BASF Aktiengesellschaft (DE) | 1992-01-02 | — | — | EP | claimed |
| US-4912220-A | Mixing a nitroaryl compound with an unsaturated silane under anhydrous conditions; adding a fluoride compound and an electrophilic compound | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-27 | — | — | US | claimed |
| US-4743690-A | NITROARYL COMPOUND, SILANE, FLUORO ONIUM COMPOUND, BROMIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-10 | — | — | US | claimed |
| EP-0030198-B1 | ISOQUINOLINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1983-03-02 | — | — | EP | claimed |
| EP-0030198-A1 | Isoquinoline derivatives, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1981-06-10 | — | — | EP | claimed |
| US-4269842-A | Method for treating rhinoviral complaints | RHONE-POULENC INDUSTRIES (FR) | 1981-05-26 | — | — | US | claimed |
| US-4261999-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | RHONE-POULENC INDUSTRIES (FR) | 1981-04-14 | — | — | US | claimed |
| US-4189480-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | RHONE-POULENC INDUSTRIES (FR) | 1980-02-19 | — | — | US | claimed |
| US-4153699-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | RHONE-POULENC INDUSTRIES (FR) | 1979-05-08 | — | — | US | claimed |
| US-4064247-A | ANALGESIC, ANTIPYRETIC | RHONE-POULENC INDUSTRIES (FR) | 1977-12-20 | — | — | US | claimed |