Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL18987372

CCCCN1CCCC1.N

nearest known ligand 0.73

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.57
GNAI3 P08754 3/20 0.46
GNAO1 P09471 3/20 0.46
GNAI1 P63096 3/20 0.46
LTA4H P09960 1/20 0.46
MAPT P10636 1/20 0.44
CARM1 Q86X55 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
PRMT8 Q9NR22 1/20 0.44
CYP1A2 P05177 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GLB1 P16278 1/20 0.43
ALDH1A1 P00352 1/20 0.41
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
S1PR5 Q9H228 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8765175 0.97 HRH3 (0.62) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL4914238 0.97
SCHEMBL28057560 0.97 HRH3 (0.60) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL172368 0.97
Ammonia Solution, Strong SCHEMBL28006868 0.95 HRH3 (0.59) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL60452 0.94 HRH3 (0.65) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL6506788 0.94 HRH3 (0.65) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL6506197 0.94 HRH3 (0.65) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL20733674 0.94 HRH3 (0.65) HRH3GNAI3GNAO1GNAI1LTA4H
Iodide SCHEMBL14953631 0.94 HRH3 (0.57) HRH3GNAI3GNAO1GNAI1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117915958-A Dendritic structures as non-viral vectors in gene delivery 蒂巴生物技术有限公司 2024-04-19 CN claimed
CN-117915958-A Dendritic structures as non-viral vectors in gene delivery 蒂巴生物技术有限公司 2024-04-19 CN disclosed
US-20190330197-A1 SUBSTITUTED NAPHTHALENE DIIMIDES AND THEIR USE UCL BUSINESS PLC (GB) 2019-10-31 US disclosed
EP-3402794-A1 SUBSTITUTED NAPHTHALENE DIIMIDES AND THEIR USE UCL Business PLC (GB) 2018-11-21 EP disclosed
WO-2017103587-A1 SUBSTITUTED NAPHTHALENE DIIMIDES AND THEIR USE UCL BUSINESS PLC (GB) 2017-06-22 WO disclosed
CN-85101682-A The preparation method of beta-lactam antibiotics and application thereof 1987-01-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330197-A1 SUBSTITUTED NAPHTHALENE DIIMIDES AND THEIR USE DDB1, RNASE1, DDX21 HRH3 3355/4885GNAI3 876/4885GNAO1 1366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.