Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18989139 | 0.88 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGASAH1 | |
| SCHEMBL18989298 | 0.82 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL18989289 | 0.81 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGASAH1 | |
| SCHEMBL18988722 | 0.79 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988992 | 0.76 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBMAPTRXFP1 | |
| SCHEMBL18988561 | 0.74 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988492 | 0.74 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988763 | 0.72 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006315 | 0.72 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988637 | 0.71 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |