Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18988763 | 0.90 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL19006161 | 0.81 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL18989298 | 0.79 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL19006274 | 0.79 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988722 | 0.75 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL18988561 | 0.75 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL18988624 | 0.74 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL19006298 | 0.74 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006282 | 0.74 | PIK3CD (0.60) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006299 | 0.73 | PIK3CD (0.70) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |