Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18989435 | 0.92 | RXRA (0.40) | TACR1CAPN1RXRARXRBRXRG | |
| SCHEMBL2546712 | 0.86 | HTR2A (0.49) | LMNA | |
| SCHEMBL17078161 | 0.85 | RXRA (0.46) | RXRARXRBRXRG | |
| SCHEMBL6344818 | 0.80 | CAPN1 (0.40) | CAPN1 | |
| SCHEMBL3292711 | 0.74 | CAPN1 (0.61) | CAPN1 | |
| SCHEMBL2369340 | 0.74 | CAPN1 (0.61) | CAPN1 | |
| SCHEMBL17865652 | 0.74 | CAPN1 (0.61) | CAPN1 | |
| SCHEMBL25382819 | 0.73 | CAPN1 (0.47) | CAPN1ALDH1A1 | |
| SCHEMBL3989376 | 0.73 | CAPN1 (0.47) | CAPN1ALDH1A1 | |
| SCHEMBL12341528 | 0.72 | ACACB (0.46) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402777-A1 | OXAZOLIDINONES AS TARO INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-11-21 | — | — | EP | disclosed |
| WO-2017106138-A1 | OXAZOLIDINONES AS TARO INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | disclosed |