Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20049050 | 0.85 | TSHR (0.54) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL13291870 | 0.80 | TSHR (0.48) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL5423335 | 0.80 | TSHR (0.48) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL3337780 | 0.80 | TSHR (0.48) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL9593664 | 0.78 | TSHR (0.50) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL24933884 | 0.77 | TSHR (0.45) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL5555166 | 0.77 | TSHR (0.45) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL17320197 | 0.77 | TACR1 (0.42) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL13922313 | 0.76 | TACR1 (0.64) | TSHRTACR1 | |
| SCHEMBL20625170 | 0.76 | TACR1 (0.44) | TSHRTACR1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11433136-B2 | Polyacetal polymers, conjugates, particles and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2022-09-06 | — | — | US | disclosed |
| US-20180360978-A1 | POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2018-12-20 | — | — | US | disclosed |
| EP-3389720-A1 | POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF | The General Hospital Corporation (US) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017106630-A1 | POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180360978-A1 | POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF | CD44, FUT6, MSN | TSHR 3897/4885TACR1 2688/4885KDM4E 4512/4885 |
| US-11433136-B2 | Polyacetal polymers, conjugates, particles and uses thereof | CD44, FUT6, MSN | TSHR 3897/4885TACR1 2688/4885KDM4E 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.