SCHEMBL1899103

SCHEMBL1899103

Nc1ccc(C(O)(c2ccc(N)cc2)c2ccc(N)cc2)cc1.Nc1cccc(N)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.55
CASP1 P29466 1/20 0.55
RECQL P46063 1/20 0.55
TSHR P16473 3/20 0.45
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CYP19A1 P11511 2/20 0.42
KDM4E B2RXH2 1/20 0.40
ENPP2 Q13822 1/20 0.40
MAOA P21397 1/20 0.38
PTGS1 P23219 2/20 0.38
HSD17B10 Q99714 1/20 0.38
F2 P00734 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1893885 0.90 CASP1 (0.44) CYP3A4CASP1RECQLTSHRMAPK1
Aniline SCHEMBL5862814 0.86 TSHR (0.55) CYP3A4TSHRALDH1A1TDP1CYP19A1
SCHEMBL301882 0.85 MAPT (0.50) CYP3A4CASP1TSHRMAPK1ALDH1A1
SCHEMBL8218323 0.81 TSHR (0.48) CYP3A4TSHRALDH1A1TDP1CYP19A1
SCHEMBL5472428 0.80 CYP3A4 (0.86) CYP3A4CASP1RECQLTSHRMAPK1
SCHEMBL29470948 0.76 CYP3A4 (0.65) CYP3A4CASP1RECQLTSHRALDH1A1
SCHEMBL12665765 0.74 ACHE (0.62) TSHRMAPK1ALDH1A1TDP1CA1
SCHEMBL11661863 0.74 CYP3A4 (1.00) CYP3A4CASP1RECQLTSHRMAPK1
SCHEMBL1934399 0.74 CYP3A4 (1.00) CYP3A4CASP1RECQLTSHRMAPK1
SCHEMBL16054 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110117431-A1 LITHIUM SECONDARY BATTERY AND METHOD OF MANUFACTURING THE SAME SANYO ELECTRIC CO., LTD. (JP) 2011-05-19 US disclosed