Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4214351 | 0.84 | — | — | |
| SCHEMBL14470773 | 0.81 | — | — | |
| SCHEMBL9577974 | 0.79 | — | — | |
| SCHEMBL15541621 | 0.79 | — | — | |
| SCHEMBL19689585 | 0.71 | PKM (0.48) | PKMLMNAALOX15BLMPMP22 | |
| SCHEMBL11788006 | 0.71 | — | — | |
| SCHEMBL23199589 | 0.69 | TSHR (0.38) | PKMCYP2C19SMN1; SMN2TDP1FFAR3 | |
| SCHEMBL12699161 | 0.69 | TSHR (0.38) | PKMCYP2C19SMN1; SMN2TDP1FFAR3 | |
| SCHEMBL16533608 | 0.69 | PKM (0.36) | PKMCYP2C19LMNASMN1; SMN2TDP1 | |
| SCHEMBL19307390 | 0.69 | FFAR3 (0.47) | PKMCYP3A4CYP2C19LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105123695-B | Soft rot control agent and Disease-Control for Soft-Rotting method | 石原产业株式会社 | 2018-03-06 | — | — | CN | claimed |
| EP-3394044-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2018-10-31 | — | — | EP | disclosed |
| CN-108430993-A | TANK-BINDING KINASE INHIBITOR COMPOUNDS | 吉利德科学公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-105050406-B | Composition comprising triazole compound | 巴斯夫农业公司 | 2017-09-15 | — | — | CN | disclosed |
| WO-2017106556-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2017-06-22 | — | — | WO | disclosed |
| CN-103012285-A | Polymorphs of 3-(e)-2-{2-[6-(2-cyanophenoxy) pyrimidin-4-yloxy]-phenyl}-3-methoxy-acrylate | MAKHTESHIM CHEM WORKS LTD (IL) | 2013-04-03 | — | — | CN | disclosed |
| CN-101621926-A | Polymorphic forms of 3- (E) -2- { 2- [ 6- (2-cyanophenoxy) pyrimidin-4-yloxy ] -phenyl } -3-methoxy-acrylate | MAKHTESHIM CHEM WORKS LTD (IL) | 2010-01-06 | — | — | CN | disclosed |
| CN-1255040-A | Method for controlling harmful fungi | BASF AG (DE) | 2000-05-31 | — | — | CN | disclosed |