SCHEMBL9577974

SCHEMBL9577974

CC1(C(N)=O)CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18992124 0.79 PKM (0.50)
SCHEMBL9592171 0.79 PKM (0.37)
SCHEMBL4214351 0.77
SCHEMBL9312275 0.77 PKM (0.31)
SCHEMBL248540 0.74
SCHEMBL14470773 0.74
SCHEMBL31487839 0.74
SCHEMBL9577996 0.74
SCHEMBL15541621 0.72
SCHEMBL231482 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638458-A1 MALT1 INHIBITORS Janssen Pharmaceutica NV (BE) 2025-10-29 EP disclosed
US-12240862-B2 Inhibitors of peptidylarginine deiminases GILEAD SCIENCES, INC. (US) 2025-03-04 US disclosed
WO-2024133859-A1 MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 WO disclosed
EP-4143195-A1 IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 Janssen Pharmaceutica NV (BE) 2023-03-08 EP disclosed
EP-3019196-B1 COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-06-06 EP disclosed
EP-2802326-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-04-18 EP disclosed
US-5264632-A Fungicide intermediate BAYER AKTIENGESELLSCHAFT (DE) 1993-11-23 US disclosed
US-5208388-A Chemical intermediates for heterocyclic fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-05-04 US disclosed
US-5095147-A Intermediates for fungicides BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed