⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375455 | 1.00 | — | — | |
| SCHEMBL27662469 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6791523 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31028710 | 0.97 | — | — | |
| SCHEMBL3364819 | 0.74 | — | — | |
| SCHEMBL63023 | 0.72 | — | — | |
| Diaminopyrimidine SCHEMBL53016 | 0.72 | — | — | |
| Diaminopyrimidine SCHEMBL29389172 | 0.72 | — | — | |
| Diaminopyrimidine SCHEMBL6013998 | 0.72 | HSP90AA1 (0.48) | — | |
| SCHEMBL29483856 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330887-A | Method for preparing drug building block 5-bromo-4-fluoropyrimidine-2-amine by one-pot method | 上海锐谱医药科技有限公司 | 2025-01-21 | — | — | CN | claimed |
| CN-117447407-B | Preparation method of JAK2 inhibitor Pacritinib and intermediate thereof | 潍坊医学院 | 2024-06-11 | — | — | CN | claimed |
| CN-117447407-A | Preparation method of JAK2 inhibitor Pacritinib and intermediate thereof | 潍坊医学院 | 2024-01-26 | — | — | CN | claimed |
| CN-115925686-A | Meridianin derivatives, coupling synthesis method and application thereof promoted by Lewis acid | 贵州医科大学 | 2023-04-07 | — | — | CN | claimed |
| CN-113549254-B | Method for preparing modified vulcanized rubber and modified vulcanized rubber | 中国科学技术大学 | 2022-10-28 | — | — | CN | claimed |
| CN-113999177-A | Preparation method of 2-amino-4, 6-dichloropyrimidine | 苏州艾缇克药物化学有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-113549254-A | Method for preparing modified vulcanized rubber and modified vulcanized rubber | 中国科学技术大学 | 2021-10-26 | — | — | CN | claimed |
| CN-109053590-A | A method of preparing the chloro- 2- aminopyrimidine of 4,6- bis- | 江苏富鼎化学有限公司 | 2018-12-21 | — | — | CN | claimed |
| US-8895747-B2 | Method and substances for preparation of N-substituted pyridinium compounds | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-11-25 | — | — | US | claimed |
| CN-102924441-A | N-(4-(4-(3-fluorophenyl)piperazin-1-yl)pyrimidin-2-yl)-amide or salts thereof, preparation method and applications | UNIV SOUTH CHINA TECH | 2013-02-13 | — | — | CN | claimed |
| US-20020055506-A1 | Methods for treatment of disease-induced peripheral neuropathy and related conditions | SPECTRUM PHARMACEUTICALS, INC. | 2002-05-09 | — | — | US | claimed |
| US-20020040032-A1 | Methods for stimulation of synthesis of synaptophysin in the central nervous system | NEOTHERAPEUTICS, INC. | 2002-04-04 | — | — | US | claimed |
| US-20020040031-A1 | Methods for prevention of accumulation of amyloid beta peptide in the central nervous system | NEO THERAPEUTICS, INC. | 2002-04-04 | — | — | US | claimed |
| WO-2002004449-A2 | METHODS FOR TREATMENT OF CONDITIONS AFFECTED BY ACTIVITY OF MULTIDRUG TRANSPORTERS | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004452-A2 | METHODS FOR TREATMENT OF DISEASE-INDUCED PERIPHERAL NEUROPATHY AND RELATED CONDITIONS | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004451-A2 | METHODS FOR STIMULATION OF SYNTHESIS OF SYNAPTOPHYSIN IN THE CENTRAL NERVOUS SYSTEM | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004450-A2 | METHODS FOR PREVENTION OF ACCUMULATION OF AMYLOID BETA PEPTIDE IN THE CENTRAL NERVOUS SYSTEM | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004448-A2 | METHODS FOR TREATMENT OF DRUG-INDUCED PERIPHERAL NEUROPATHY AND RELATED CONDITIONS | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | claimed |
| EP-0644882-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1995-03-29 | — | — | EP | claimed |
| WO-1993025539-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | claimed |