Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011533 | 0.87 | MAPK1 (0.42) | KDM4ERAB9AHTTMAPK1ALDH1A1 | |
| SCHEMBL14810517 | 0.87 | MAPK1 (0.51) | MAPK1 | |
| SCHEMBL18993123 | 0.76 | NPC1 (0.43) | KDM4ENPC1RAB9AGAAMAPT | |
| SCHEMBL18993122 | 0.76 | KDM4E (0.43) | KDM4ENPC1RAB9AGAAMAPT | |
| SCHEMBL1012147 | 0.76 | MAPK1 (0.61) | MAPTMAPK1 | |
| SCHEMBL27233649 | 0.75 | ALDH1A1 (0.43) | KDM4ENPC1RAB9AGAAMAPT | |
| SCHEMBL1012278 | 0.74 | MAPK1 (0.50) | MAPTMAPK1L3MBTL1 | |
| SCHEMBL30903848 | 0.74 | MAPK1 (0.41) | KDM4EHTTMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL27233677 | 0.74 | MAPK1 (0.44) | KDM4ERAB9AGAAMAPTHTT | |
| SCHEMBL1037249 | 0.74 | FAAH (0.41) | KDM4EHTTMAPK1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |