Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | TOP1 | P11387 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616929 | 0.88 | AURKB (0.68) | AURKBMEN1KMT2ARAB9ATOP1 | |
| SCHEMBL28707478 | 0.87 | AURKB (0.67) | AURKBMEN1KMT2ARAB9ATOP1 | |
| SCHEMBL18027770 | 0.87 | AURKB (0.67) | AURKBMEN1KMT2ARAB9ATOP1 | |
| SCHEMBL8348359 | 0.85 | AURKB (0.64) | AURKBMEN1KMT2ARAB9ATOP1 | |
| SCHEMBL10904567 | 0.85 | AURKB (0.72) | AURKBMEN1KMT2ARAB9ASLC22A6 | |
| SCHEMBL18993437 | 0.84 | MEN1 (0.54) | AURKBMEN1KMT2ARAB9APKM | |
| SCHEMBL13293386 | 0.84 | AURKB (0.63) | AURKBMEN1KMT2ARAB9ASLC22A6 | |
| SCHEMBL18010194 | 0.82 | AURKB (0.61) | AURKBMEN1KMT2ARAB9ATOP1 | |
| SCHEMBL29066077 | 0.81 | ATM (0.64) | AURKBMEN1KMT2ARAB9ASLC22A6 | |
| SCHEMBL18993399 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2ARAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682931-B2 | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof | UBE INDUSTRIES, LTD. (JP) | 2017-06-20 | — | — | US | disclosed |