Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18027796 | 0.84 | RAB9A (0.56) | F2RNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL893100 | 0.83 | F2R (0.64) | F2RNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16692739 | 0.80 | F2R (0.48) | F2RBACE1NPC1RAB9AKDM4E | |
| SCHEMBL18207855 | 0.77 | GRM5 (0.52) | F2RBACE1NPC1RAB9AKDM4E | |
| SCHEMBL7783276 | 0.76 | MAOB (0.51) | F2RBACE1NPC1RAB9AKDM4E | |
| SCHEMBL4781928 | 0.75 | SMN1; SMN2 (0.59) | F2RBACE1NPC1RAB9AKDM4E | |
| SCHEMBL15707278 | 0.75 | CA1 (0.52) | F2RBACE1 | |
| SCHEMBL18207867 | 0.74 | KMT2A (0.57) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL15886276 | 0.74 | BACE1 (0.54) | F2RBACE1NPC1RAB9AALDH1A1 | |
| SCHEMBL25683741 | 0.74 | ALDH1A1 (0.55) | F2RBACE1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682931-B2 | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof | UBE INDUSTRIES, LTD. (JP) | 2017-06-20 | — | — | US | disclosed |