Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772217 | 0.82 | POLB (0.54) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL6037515 | 0.82 | NPC1 (0.43) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL6037520 | 0.82 | RAB9A (0.67) | NPC1RAB9AMEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL31228747 | 0.81 | PTPN1 (0.58) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL6954756 | 0.81 | PTPN1 (0.58) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL8826894 | 0.81 | NPC1 (0.63) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL8537614 | 0.81 | NPC1 (0.63) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL28476840 | 0.79 | TOP1 (0.55) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL16416801 | 0.79 | KDM4E (0.67) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL16692745 | 0.78 | TRPV4 (0.43) | NPC1RAB9AMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682931-B2 | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof | UBE INDUSTRIES, LTD. (JP) | 2017-06-20 | — | — | US | disclosed |