Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20780329 | 0.77 | SLC6A3 (0.31) | SLC6A3DRD2HTR2AHRH1ALDH1A1 | |
| SCHEMBL23153545 | 0.76 | SLC6A3 (0.31) | SLC6A3DRD2HTR2AHRH1 | |
| SCHEMBL23729956 | 0.75 | SLC6A3 (0.36) | SLC6A3DRD2HTR2AHRH1PIK3CD | |
| SCHEMBL20259466 | 0.73 | SLC6A3 (0.32) | SLC6A3DRD2HTR2AHRH1 | |
| SCHEMBL179319 | 0.72 | CCR4 (0.39) | SLC6A3DRD2HTR2AHRH1PIK3CD | |
| SCHEMBL20086447 | 0.70 | SLC6A3 (0.32) | SLC6A3DRD2HTR2AHRH1 | |
| SCHEMBL23846748 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL22824973 | 0.69 | SLC6A3 (0.35) | SLC6A3DRD2HTR2AHRH1PIK3CD | |
| SCHEMBL22895153 | 0.68 | HMGCR (0.33) | SLC6A3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20738457 | 0.67 | SLC6A3 (0.34) | SLC6A3DRD2HTR2AHRH1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682983-B2 | BMP inhibitors and methods of use thereof | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-06-20 | — | — | US | disclosed |