Triaziquone

Triaziquone

SCHEMBL1899562

CCC(CO)(CO)CO.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
TP53 P04637 1/20 0.36
STAT3 P40763 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
DNMT1 P26358 1/20 0.35
NSD2 O96028 1/20 0.32
TTR P02766 1/20 0.32
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL8396041 0.93 TP53 (0.33) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL11350903 0.87 HTT (0.42) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL1567806 0.85 DNMT1 (0.35) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL5606305 0.84 HTT (0.42) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL17609997 0.83 MAPT (0.37) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL21358774 0.82 MAPT (0.43) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL8429242 0.82 MAPT (0.36) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL7783197 0.82 MAPT (0.46) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL7734974 0.81 MAPT (0.38) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL93807 0.81 DNMT1 (0.37) MAPTHTTTP53STAT3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436084-B2 Aqueous coating composition and method for forming multilayer coating film KANSAI PAINT CO., LTD. (JP) 2013-05-07 US disclosed
US-20110117378-A1 AQUEOUS COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2011-05-19 US disclosed
WO-2010007891-A1 AQUEOUS COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2010-01-21 WO disclosed