Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21579301 | 0.89 | TP53 (0.37) | TP53HTTL3MBTL1POLBLMNA | |
| SCHEMBL26504917 | 0.79 | HRH3 (0.38) | HRH3 | |
| SCHEMBL19867105 | 0.77 | TP53 (0.39) | TP53HTTL3MBTL1POLBTDP1 | |
| SCHEMBL18799820 | 0.76 | POLB (0.36) | TP53HTTL3MBTL1POLBTDP1 | |
| SCHEMBL22224668 | 0.76 | POLB (0.37) | TP53HTTL3MBTL1POLBTDP1 | |
| SCHEMBL18799869 | 0.76 | POLB (0.37) | TP53HTTL3MBTL1POLBTDP1 | |
| SCHEMBL21880995 | 0.75 | GNAI3 (0.37) | HRH1 | |
| SCHEMBL4569268 | 0.72 | TP53 (0.46) | TP53HTTL3MBTL1POLBLMNA | |
| SCHEMBL21790509 | 0.72 | TDP1 (0.38) | TP53POLBTDP1ALDH1A1ATM | |
| SCHEMBL21881668 | 0.72 | GNAO1 (0.40) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682141-B2 | Combination of kinase inhibitors and uses thereof | INTELLIKINE LLC (US) | 2017-06-20 | — | — | US | disclosed |