Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEDD4 | P46934 | 1/20 | 0.86 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141990 | 0.93 | NEDD4 (1.00) | NEDD4PKMLMNAMAPTALDH1A1 | |
| SCHEMBL17141988 | 0.91 | NEDD4 (0.83) | NEDD4PKMLMNAMAPTALDH1A1 | |
| SCHEMBL18996018 | 0.87 | NEDD4 (0.81) | NEDD4LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18996017 | 0.85 | LMNA (0.73) | NEDD4LMNAMAPTRXFP1TP53 | |
| SCHEMBL17141933 | 0.84 | NEDD4 (0.79) | NEDD4PKMLMNAMAPTALDH1A1 | |
| SCHEMBL17141961 | 0.83 | NEDD4 (0.78) | NEDD4PKMLMNAMAPTALDH1A1 | |
| SCHEMBL17141981 | 0.82 | NEDD4 (0.76) | NEDD4PKMLMNAMAPTALDH1A1 | |
| SCHEMBL17142013 | 0.82 | NEDD4 (0.69) | NEDD4PKMLMNAMAPTALDH1A1 | |
| SCHEMBL17141916 | 0.81 | NEDD4 (0.72) | NEDD4LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17141919 | 0.81 | NEDD4 (0.71) | NEDD4LMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | Rhe Trustees of The University of Pennsylvania | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | ZC3HAV1, MAVS, ZC3HAV1L | NEDD4 2641/4885PKM 3984/4885LMNA 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.