SCHEMBL1899751

SCHEMBL1899751

O=P(O)(Oc1ccc(Br)cc1Br)Oc1ccc(Br)cc1Br

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.54
ALDH1A1 P00352 3/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
SMN1; SMN2 Q16637 5/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 2/20 0.47
HPGD P15428 2/20 0.47
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
TSHR P16473 1/20 0.47
ALOX15 P16050 6/20 0.44
ALOX12 P18054 2/20 0.43
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
HTR1B P28222 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8807840 0.89 ALDH1A1 (0.47) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL27306109 0.89 MAPK1 (0.47) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL4370189 0.88 MAPK1 (0.54) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL27746698 0.86 MAPK1 (0.52) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL544629 0.83 MAPK1 (0.58) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL29378605 0.83 MAPK1 (0.58) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL7632227 0.82 SMN1; SMN2 (0.38) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL12006590 0.82 MAPK1 (0.47) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL8926339 0.80 MAPK1 (0.54) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
Potassium Ion SCHEMBL2001395 0.78 MAPK1 (0.52) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2492315-B1 AROMATIC POLYCARBONATE RESIN COMPOSITION TEIJIN CHEMICALS LTD (JP) 2020-06-10 EP disclosed
EP-2243627-B1 POLYCARBONATE RESIN LAYERED SHEET TEIJIN CHEMICALS LTD (JP) 2013-09-18 EP disclosed
US-8501303-B2 Aromatic polycarbonate resin composition TEIJIN CHEMICALS, LTD. (JP) 2013-08-06 US disclosed
US-20120251785-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION TEIJIN CHEMICALS, LTD. (JP) 2012-10-04 US disclosed
EP-2492315-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION Teijin Chemicals, Ltd. (JP) 2012-08-29 EP disclosed
EP-2319887-A1 METHOD FOR MANUFACTURING MOLDED ARTICLE Teijin Chemicals, Ltd. (JP) 2011-05-11 EP disclosed
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed
EP-1489123-A1 COPOLYCARBONATE AND HEAT-RESISTANT PART COMPRISING THE COPOLYMER Teijin Chemicals, Ltd. (JP) 2004-12-22 EP disclosed
EP-1300445-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION Teijin Chemicals, Ltd. (JP) 2003-04-09 EP disclosed
US-4083789-A METAL COMPOUND AS REACTIVE MODIFIER MONSANTO COMPANY (US) 1978-04-11 US disclosed