Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | INPPL1 | O15357 | 11/20 | 0.52 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.52 |
| ▸ | INPP5B | P32019 | 2/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27746698 | 0.98 | MAPK1 (0.52) | MAPK1ALDH1A1TDP1L3MBTL1INPPL1 | |
| SCHEMBL1899751 | 0.88 | MAPK1 (0.54) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL544629 | 0.83 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL29378605 | 0.83 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL12006590 | 0.82 | MAPK1 (0.47) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL27306109 | 0.82 | MAPK1 (0.47) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL8807840 | 0.82 | ALDH1A1 (0.47) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL13343010 | 0.81 | INPPL1 (0.48) | ALDH1A1INPPL1INPP5AINPP5BAKT1 | |
| SCHEMBL11360950 | 0.81 | INPPL1 (0.48) | ALDH1A1TDP1L3MBTL1INPPL1INPP5A | |
| SCHEMBL8926339 | 0.80 | MAPK1 (0.54) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586521-A | One kind three（2,4- dibromo phenyls）The preparation method of phosphate | 潍坊玉成化工有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-103756254-B | Epoxy resin for liquid oxygen environment and preparation method and application thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-104725789-A | High-performance low-cost flame-retardant PET/ABS composite material | QINGDAO WANLI TECHNOLOGY CO LTD | 2015-06-24 | — | — | CN | claimed |
| CN-104672861-A | Flame-retardant anti-aging PC (polycarbonate) composite material and preparation method thereof | QINGDAO JIAYIYANG INDUSTRY & TRADE CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-104419163-A | High-impact-resistance modified PC composite material | QINGDAO XINZHAN PLASTIC CO LTD | 2015-03-18 | — | — | CN | claimed |
| CN-104341732-A | High-performance toughened flame retardant PET (polyethylene terephthalate)/ABS (acrylonitrile-butadiene-styrene) alloy and preparation method | QINGDAO XINZHAN PLASTIC CO LTD | 2015-02-11 | — | — | CN | claimed |
| CN-103756254-A | Epoxy resin for liquid oxygen environment and preparation method and application thereof | UNIV DALIAN TECH | 2014-04-30 | — | — | CN | claimed |
| CN-103709716-A | Anti-static, toughening and flame-retardant master batch | QINGDAO XINZHAN PLASTIC CO LTD | 2014-04-09 | — | — | CN | claimed |
| JP-3739785-B2 | — | — | 2006-01-25 | — | — | JP | claimed |
| US-20040265802-A9 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | FROEHLER BRIAN (US) | 2004-12-30 | — | — | US | claimed |
| US-5645985-A | USED FOR DIAGNOSIS TO DETECT VIRUSES OR DISEASED CONDITIONS | GILEAD SCIENCES, INC. (US) | 1997-07-08 | — | — | US | claimed |
| US-5594121-A | DETECT VIRUSES, DISEASES | GILEAD SCIENCES, INC. (US) | 1997-01-14 | — | — | US | claimed |
| EP-0695306-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PURINES | GILEAD SCIENCES, INC. (US) | 1996-02-07 | — | — | EP | claimed |
| EP-0637965-A4 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES. | GILEAD SCIENCES INC (US) | 1996-01-24 | — | — | EP | claimed |
| EP-0637965-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1995-02-15 | — | — | EP | claimed |
| EP-0616612-A4 | NUCLEASE STABLE AND BINDING COMPETENT OLIGOMERS AND METHODS FOR THEIR USE. | GILEAD SCIENCES INC (US) | 1995-01-11 | — | — | EP | claimed |
| WO-1994024144-A2 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PURINES | GILEAD SCIENCES, INC. (US) | 1994-10-27 | — | — | WO | claimed |
| EP-0616612-A1 | NUCLEASE STABLE AND BINDING COMPETENT OLIGOMERS AND METHODS FOR THEIR USE | GILEAD SCIENCES, INC. (US) | 1994-09-28 | — | — | EP | claimed |
| WO-1993012135-A1 | NUCLEASE STABLE AND BINDING COMPETENT OLIGOMERS AND METHODS FOR THEIR USE | GILEAD SCIENCES, INC. (US) | 1993-06-24 | — | — | WO | claimed |
| WO-1993010820-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1993-06-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040265802-A9 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | NUDT1, DHX15, DDX5 | MAPK1 4599/4885ALDH1A1 2011/4885TDP1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.