SCHEMBL1899759

SCHEMBL1899759

NC(=O)C/C=C/CC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
ALOX15 P16050 3/20 0.47
CYP2D6 P10635 1/20 0.47
LMNA P02545 4/20 0.41
BLM P54132 4/20 0.41
KDM4E B2RXH2 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
TP53 P04637 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C19 P33261 2/20 0.41
PMP22 Q01453 2/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
THPO P40225 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14842937 1.00 ALDH1A1 (0.47) ALDH1A1ALOX15CYP2D6LMNABLM
Ethylene SCHEMBL11644945 0.93 ALDH1A1 (0.42) ALDH1A1ALOX15CYP2D6LMNABLM
Ethylene SCHEMBL11644957 0.93 ALDH1A1 (0.42) ALDH1A1ALOX15CYP2D6LMNABLM
SCHEMBL3977045 0.85
SCHEMBL293277 0.85
SCHEMBL293276 0.85
SCHEMBL8632835 0.85
SCHEMBL3977043 0.85
SCHEMBL11937917 0.85
SCHEMBL4564186 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1813630-B1 Encapsulated Michael addition catalyst ROHM & HAAS (US) 2010-03-03 EP claimed
WO-2023093517-A1 SOLID-STATE ELECTROLYTE AND SECONDARY BATTERY 深圳新宙邦科技股份有限公司 2023-06-01 WO disclosed
EP-3281931-A1 METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS Elevance Renewable Sciences, Inc. (US) 2018-02-14 EP disclosed
US-9481643-B2 Fluorosurfactants MERCK PATENT GMBH (DE) 2016-11-01 US disclosed
US-20150246875-A1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2015-09-03 US disclosed
EP-2325167-A1 METHOD FOR PRODUCING CARBAMATE COMPOUND Ube Industries, Ltd. (JP) 2011-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246875-A1 FLUOROSURFACTANTS FPR3, Q6ZSR9, FLNB ALDH1A1 2256/4885ALOX15 1804/4885CYP2D6 2941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.