⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093463 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL6650487 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL1802869 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL983991 | 0.92 | MEN1 (0.52) | — | |
| SCHEMBL128554 | 0.92 | TSHR (0.52) | — | |
| SCHEMBL983735 | 0.89 | THRB (0.56) | — | |
| SCHEMBL816140 | 0.89 | TSHR (0.50) | — | |
| SCHEMBL816279 | 0.89 | TSHR (0.50) | — | |
| SCHEMBL816971 | 0.89 | TSHR (0.50) | — | |
| SCHEMBL983489 | 0.89 | THRB (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4019 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354999-A | Pyridazine-1 (6H) -6-oxo compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| WO-2024120457-A1 | PYRROLO[3,2-D]PYRIMIDIN-4-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2024-06-13 | — | — | WO | claimed |
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| US-20240166627-A1 | Terpyridinedione compound or salt thereof, and preparation method and application thereof | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2024-05-23 | — | — | US | claimed |
| CN-117712476-A | Gel quasi-solid electrolyte and lithium battery prepared from same | 湖南大学 | 2024-03-15 | — | — | CN | claimed |
| CN-116648244-B | Terpyridyl dione compound or salt thereof, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-117100752-A | Medical use of glucagon-like peptide-1 (GLP-1) receptor agonists | 深圳信立泰药业股份有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| EP-4242202-A1 | BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2023-09-13 | — | — | EP | claimed |
| CN-116731013-A | Heterocyclic compound, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-09-12 | — | — | CN | claimed |
| EP-0670838-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-09-13 | — | — | EP | claimed |
| WO-1995018126-A1 | FURYLTHIAZOLE AND THEIR USE AS H2-RECEPTOR ANTAGONISM AND ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | claimed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | claimed |
| WO-1994017063-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| US-5321057-A | Ammonium polyphosphate microencapsulated with aminoplastic resins | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-06-14 | — | — | US | claimed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | claimed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | claimed |
| US-5190689-A | Polymer materials having liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | claimed |
| US-4894181-A | Carbocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-01-16 | — | — | US | claimed |
| US-4758373-A | Carbocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-19 | — | — | US | claimed |