Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 14/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431860 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL18818613 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL18537661 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL428803 | 0.77 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL13186361 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL15788373 | 0.74 | ALDH1A1 (0.79) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL17791874 | 0.73 | MAPT (0.62) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL428713 | 0.72 | MAPT (1.00) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL13186294 | 0.71 | MAPT (0.77) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL429191 | 0.71 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181568-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |