SCHEMBL19001499

SCHEMBL19001499

Ic1cccc2c1-c1ccccc1C21c2ccccc2-c2c1ccc1ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.37
PTPN1 P18031 1/20 0.34
ALDH1A1 P00352 4/20 0.33
MAPT P10636 4/20 0.33
HSD17B10 Q99714 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
TSHR P16473 2/20 0.33
CYP2A6 P11509 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
NSD2 O96028 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
DHFR P00374 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19141145 0.88 DNMT1 (0.35) DNMT1PTPN1ALDH1A1MAPTHSD17B10
SCHEMBL19974142 0.87 DNMT1 (0.43) DNMT1PTPN1ALDH1A1MAPTHSD17B10
SCHEMBL29473425 0.87 DNMT1 (0.43) DNMT1PTPN1ALDH1A1MAPTHSD17B10
SCHEMBL18392094 0.83 KDM4E (0.39) MAPTMEN1KMT2ATSHRTDP1
SCHEMBL20914937 0.81 DNMT1 (0.44) DNMT1PTPN1ALDH1A1MAPTHSD17B10
SCHEMBL23280663 0.81 PDK2 (0.45) DNMT1ALDH1A1MAPTHSD17B10MEN1
SCHEMBL19822216 0.81 PDK2 (0.45) DNMT1ALDH1A1MAPTHSD17B10MEN1
SCHEMBL19668064 0.81 PDK2 (0.45) DNMT1PTPN1ALDH1A1MAPTHSD17B10
SCHEMBL19980565 0.81 DNMT1 (0.37) DNMT1ALDH1A1MAPTHSD17B10MEN1
SCHEMBL19683809 0.79 CYP1A2 (0.42) DNMT1PTPN1ALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11696496-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11192858-B2 Diamine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-12-07 US disclosed
US-10756274-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 US disclosed
US-20190284137-A1 DIAMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-19 US disclosed
US-20180053898-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-22 US disclosed
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170179401-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179204-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179395-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284137-A1 DIAMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AOC1, DDC, DDT DNMT1 300/4885PTPN1 4690/4885ALDH1A1 38/4885
US-11192858-B2 Diamine-based compound and organic light-emitting device including the same AOC1, DDC, DDT DNMT1 300/4885PTPN1 4690/4885ALDH1A1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.