Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEDD4 | P46934 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141994 | 0.82 | NEDD4 (1.00) | NEDD4ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL17141992 | 0.78 | NEDD4 (0.71) | NEDD4ALDH1A1KMT2ANPSR1LMNA | |
| SCHEMBL17142016 | 0.76 | NEDD4 (0.82) | NEDD4ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL17141980 | 0.73 | GAA (0.60) | ALDH1A1KMT2AMEN1NPSR1TSHR | |
| SCHEMBL17142014 | 0.72 | NEDD4 (0.76) | NEDD4ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL17142002 | 0.71 | NEDD4 (0.76) | NEDD4ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL18996015 | 0.67 | NEDD4 (0.64) | NEDD4ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL18996008 | 0.66 | NEDD4 (0.62) | NEDD4ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL3456750 | 0.63 | NPC1 (0.60) | ALDH1A1KMT2AMEN1TSHRMAPK1 | |
| SCHEMBL17141932 | 0.63 | NEDD4 (0.58) | NEDD4ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | Rhe Trustees of The University of Pennsylvania | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | ZC3HAV1, MAVS, ZC3HAV1L | NEDD4 2641/4885ALDH1A1 3536/4885KMT2A 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.