Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEDD4 | P46934 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | UBE2M | P61081 | 7/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554488 | 0.81 | SMN1; SMN2 (0.64) | NEDD4SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL18996015 | 0.80 | NEDD4 (0.64) | NEDD4SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL17141992 | 0.79 | NEDD4 (0.71) | NEDD4SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL18996014 | 0.79 | NEDD4 (0.57) | NEDD4SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL17141932 | 0.78 | NEDD4 (0.58) | NEDD4SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL17141928 | 0.78 | NEDD4 (0.56) | NEDD4SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL17141994 | 0.77 | NEDD4 (1.00) | NEDD4SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL18658188 | 0.76 | UBE2M (0.78) | SMN1; SMN2ALDH1A1KMT2AGAALMNA | |
| SCHEMBL7931954 | 0.75 | UBE2M (0.70) | SMN1; SMN2ALDH1A1KMT2AGAALMNA | |
| SCHEMBL5306485 | 0.75 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | Rhe Trustees of The University of Pennsylvania | 2017-06-22 | — | — | US | disclosed |
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | Rhe Trustees of The University of Pennsylvania | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | ZC3HAV1, MAVS, ZC3HAV1L | NEDD4 2641/4885SMN1; SMN2 536/4885ALDH1A1 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.