Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23880686 | 0.92 | PYGL (0.33) | PYGLSMN1; SMN2HPGDHTT | |
| SCHEMBL18666775 | 0.92 | PYGL (0.33) | PYGLSMN1; SMN2HPGDHTT | |
| SCHEMBL18885626 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL28600185 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL23751331 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL12197747 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL18532465 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL13056639 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL22202997 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL19643024 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10293055-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-21 | — | — | US | disclosed |
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | PYGL 605/4885SMN1; SMN2 4722/4885HPGD 608/4885 |
| US-10293055-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | AADAC, EPCAM, DCLRE1A | PYGL 605/4885SMN1; SMN2 4722/4885HPGD 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.