Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424621 | 0.84 | PNMT (0.66) | PNMTSLC6A2SLC6A3SLC6A4ALOX15 | |
| SCHEMBL6126069 | 0.84 | PNMT (0.50) | PNMTALDH1A1NPSR1CYP3A4EPHX2 | |
| SCHEMBL5950406 | 0.81 | PNMT (0.47) | PNMTALDH1A1CYP3A4KDM4ESLC6A2 | |
| SCHEMBL28747785 | 0.79 | PNMT (0.46) | PNMTCYP3A4KDM4ESLC6A2SLC6A3 | |
| SCHEMBL2165343 | 0.79 | KDM6B (0.56) | PNMTALDH1A1NPSR1CCR2EPHX2 | |
| SCHEMBL2165350 | 0.79 | KDM6B (0.56) | PNMTALDH1A1NPSR1CCR2EPHX2 | |
| SCHEMBL18387301 | 0.77 | PNMT (0.43) | PNMTALDH1A1NPSR1CYP3A4CCR2 | |
| SCHEMBL11455220 | 0.77 | PNMT (0.47) | PNMTALDH1A1NPSR1CYP3A4EPHX2 | |
| SCHEMBL7604505 | 0.77 | GABRA1 (0.52) | ALDH1A1ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL22122819 | 0.76 | PNMT (0.46) | PNMTALDH1A1CYP3A4KDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170173223-A1 | BIOLOGICALLY INERT COATING FOR IMPLANTABLE MEDICAL DEVICES | CARDIAC PACEMAKERS, INC. | 2017-06-22 | — | — | US | disclosed |