Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2965433 | 0.85 | TRPA1 (0.47) | ACHETAAR1IDO1TRPA1ALDH1A1 | |
| SCHEMBL9748682 | 0.81 | TAAR1 (0.43) | ACHETAAR1IDO1ALDH1A1CYP2D6 | |
| SCHEMBL9749502 | 0.80 | MAOB (0.45) | ACHETAAR1IDO1ALDH1A1CYP2D6 | |
| SCHEMBL17461297 | 0.80 | ACHE (0.50) | ACHETAAR1IDO1ALDH1A1CYP2D6 | |
| SCHEMBL29941639 | 0.79 | ACHE (0.55) | ACHETAAR1IDO1MAOBHRH3 | |
| SCHEMBL758533 | 0.79 | ACHE (0.55) | ACHETAAR1IDO1MAOBHRH3 | |
| SCHEMBL9427268 | 0.77 | TRPA1 (0.64) | TAAR1TRPA1CYP2D6MAOA | |
| SCHEMBL20752033 | 0.76 | ACHE (0.50) | ACHETAAR1IDO1CYP2D6MAOB | |
| SCHEMBL2258137 | 0.76 | TAAR1 (0.59) | ACHETAAR1IDO1ALDH1A1MAOB | |
| SCHEMBL2259568 | 0.76 | ACHE (0.50) | ACHETAAR1IDO1MAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170173223-A1 | BIOLOGICALLY INERT COATING FOR IMPLANTABLE MEDICAL DEVICES | CARDIAC PACEMAKERS, INC. | 2017-06-22 | — | — | US | disclosed |