SCHEMBL19001696

SCHEMBL19001696

C=C1c2ccccc2-c2cc(Br)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 2/20 0.57
S100A4 P26447 1/20 0.48
CYP1A2 P05177 2/20 0.40
MAPK1 P28482 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP2A6 P11509 1/20 0.39
PDK2 Q15119 1/20 0.38
BCL2 P10415 2/20 0.37
METAP1 P53582 1/20 0.37
MCL1 Q07820 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
AHR P35869 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13828210 0.95 PTPRC (0.57) PTPRCS100A4CYP1A2MAPK1L3MBTL1
SCHEMBL26112719 0.88 PTPRC (0.70) PTPRCS100A4CYP1A2MAPK1L3MBTL1
SCHEMBL7866191 0.88 PTPRC (0.70) PTPRCS100A4CYP1A2MAPK1L3MBTL1
SCHEMBL205625 0.85 S100A4 (0.56) PTPRCS100A4MAPK1L3MBTL1TDP1
SCHEMBL13896688 0.84 PTPRC (0.71) PTPRCS100A4CYP1A2MAPK1L3MBTL1
SCHEMBL29997437 0.80 S100A4 (0.68) PTPRCS100A4MAPK1L3MBTL1TDP1
SCHEMBL17923653 0.77 PTPRC (0.57) PTPRCS100A4CYP1A2MAPK1L3MBTL1
SCHEMBL29524280 0.77 PTPRC (0.83) PTPRCS100A4CYP1A2MAPK1L3MBTL1
SCHEMBL3948979 0.77 PTPRC (0.91) PTPRCS100A4CYP1A2MAPK1L3MBTL1
SCHEMBL30523603 0.77 PTPRC (0.83) PTPRCS100A4CYP1A2MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed