Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445191 | 0.80 | PDK2 (0.32) | — | |
| SCHEMBL1820304 | 0.77 | CYP2A6 (0.35) | CYP2A6 | |
| SCHEMBL19296324 | 0.71 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL22208367 | 0.69 | SMN1; SMN2 (0.36) | CYP2A6 | |
| SCHEMBL30362436 | 0.68 | MRGPRX1 (0.33) | — | |
| SCHEMBL8274148 | 0.68 | MRGPRX1 (0.33) | — | |
| SCHEMBL19699901 | 0.65 | CYP2A6 (0.34) | CYP2A6 | |
| SCHEMBL7926335 | 0.65 | ALDH1A1 (0.40) | CYP2A6 | |
| SCHEMBL25822916 | 0.65 | CYP2A6 (0.39) | CYP2A6 | |
| SCHEMBL7923181 | 0.64 | KDM4E (0.41) | CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320904-A2 | AMINOPYRIMIDINE INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE | Kalypsys, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010030757-A2 | AMINOPYRIMIDINE INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE | KALYPSYS INC. (US) | 2010-03-18 | — | — | WO | disclosed |