Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | LIPC | P11150 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134525 | 0.85 | HPGD (0.47) | HRH3LIPCLIPGMAPTHPGD | |
| SCHEMBL6134785 | 0.85 | MAPT (0.50) | LIPCLIPGMAPTHPGDTSHR | |
| SCHEMBL6134206 | 0.81 | HDAC3 (0.47) | LIPCLIPGMAPTHPGDTSHR | |
| SCHEMBL6134511 | 0.81 | ALDH1A1 (0.47) | LIPCLIPGMAPTHPGDTSHR | |
| SCHEMBL6133632 | 0.81 | HDAC3 (0.48) | LIPCLIPGMAPTHPGDTSHR | |
| SCHEMBL18987003 | 0.80 | BCHE (0.47) | HRH3MAPTSMN1; SMN2GAARAB9A | |
| SCHEMBL6134832 | 0.78 | HDAC3 (0.49) | LIPCLIPGMAPTHPGDTSHR | |
| SCHEMBL6135503 | 0.78 | CSNK2A2 (0.52) | HRH3LIPCLIPGUSP2 | |
| SCHEMBL18987371 | 0.78 | USP2 (0.51) | HRH3MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL19002044 | 0.78 | USP2 (0.69) | HRH3MAPTHPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103615-A1 | COMBINATION PRODUCT | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2017-06-22 | — | — | WO | disclosed |