Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738718 | 0.83 | SMN1; SMN2 (0.51) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL12058781 | 0.83 | POLB (0.52) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL6839505 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL13865731 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL10891097 | 0.80 | RECQL (0.50) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL470928 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL12431740 | 0.79 | POLB (0.48) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL9071079 | 0.79 | ALDH1A1 (0.49) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL13865733 | 0.76 | POLB (0.56) | ALDH1A1POLBRECQLMAPTKMT2A | |
| SCHEMBL19002132 | 0.76 | OGA (0.47) | ALDH1A1POLBKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106254-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | disclosed |