Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 17/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002116 | 0.76 | ALDH1A1 (0.46) | OGAALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL12058781 | 0.75 | POLB (0.52) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL9738718 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL9071079 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL6839505 | 0.74 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL13865731 | 0.74 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL10891097 | 0.72 | RECQL (0.50) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL470928 | 0.72 | SMN1; SMN2 (0.58) | OGAALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL12431740 | 0.71 | POLB (0.48) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL22957185 | 0.71 | OGA (0.67) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106254-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | disclosed |