Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002122 | 0.97 | ELANE (0.37) | ELANEMTNR1AMTNR1BRAB9AHPGD | |
| SCHEMBL24588580 | 0.88 | ELANE (0.39) | ELANEHPGDMAPTTHRBTGM2 | |
| SCHEMBL18568309 | 0.86 | ELANE (0.30) | ELANE | |
| SCHEMBL22873515 | 0.85 | MTNR1A (0.33) | MTNR1AMTNR1BRAB9AMAPTTGM2 | |
| SCHEMBL18568676 | 0.82 | ESR1 (0.33) | — | |
| SCHEMBL22415882 | 0.81 | LMNA (0.36) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL20904224 | 0.81 | MAPT (0.49) | MAPTTHRBHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL22338736 | 0.80 | MEN1 (0.36) | MTNR1AMTNR1BRAB9AHPGDMAPT | |
| SCHEMBL19002152 | 0.80 | ESR1 (0.31) | — | |
| SCHEMBL20243550 | 0.79 | MTNR1A (0.45) | MTNR1AMTNR1BMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170175078-A1 | CELL CULTURE SUBSTRATE COMPRISING FLUORINE-CONTAINING POLYMER ON ITS SURFACE | NIPPON SHOKUBAI, CO., LTD. (JP) | 2017-06-22 | — | — | US | disclosed |