SCHEMBL19002138

SCHEMBL19002138

CP(C)(=O)c1ccc(-c2cccc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4ccccc34)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GSTP1 P09211 1/20 0.37
SIRT2 Q8IXJ6 5/20 0.36
PLAU P00749 3/20 0.36
CYP17A1 P05093 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
PDE9A O76083 1/20 0.36
ALOX5 P09917 1/20 0.36
UTRN P46939 1/20 0.36
FASN P49327 1/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18904885 0.91 HSD17B1 (0.41) HSD17B1HSD17B2ESR1ESR2CA1
SCHEMBL18893211 0.91 ESR1 (0.40) HSD17B1HSD17B2ESR1ESR2CA1
SCHEMBL18892993 0.91 GSTP1 (0.41) ESR1ESR2CA1CA2CA9
SCHEMBL18892994 0.88 HSD17B1 (0.40) HSD17B1HSD17B2ESR1ESR2GSTP1
SCHEMBL29452786 0.88 HSD17B1 (0.40) HSD17B1HSD17B2ESR1ESR2GSTP1
SCHEMBL19002146 0.88 ACHE (0.36) ESR1CA2CA9
SCHEMBL20089186 0.87 HSD17B1 (0.42) HSD17B1HSD17B2ESR1ESR2CA1
SCHEMBL18892960 0.86 HSD17B1 (0.40) HSD17B1HSD17B2ESR1ESR2CA1
SCHEMBL18893036 0.85 GSTP1 (0.39) ESR1ESR2CA1CA2CA9
SCHEMBL21922666 0.85 HSD17B1 (0.39) HSD17B1HSD17B2ESR1ESR2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3355378-B1 ELECTROLUMINESCENT DEVICE COMPRISING A DEFINED LAYER ARRANGEMENT COMPRISING A LIGHT EMITTING LAYER, A HOLE TRANSPORT LAYER AND AN ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2022-12-28 EP disclosed
US-11411195-B2 Electroluminescent device comprising a defined layer arrangement comprising a light emitting layer, a hole transport layer and an electron transport layer NOVALED GMBH (DE) 2022-08-09 US disclosed
EP-3355378-A1 ELECTROLUMINESCENT DEVICE COMPRISING A DEFINED LAYER ARRANGEMENT COMPRISING A LIGHT EMITTING LAYER, A HOLE TRANSPORT LAYER AND AN ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2018-08-01 EP disclosed
WO-2017102822-A1 ELECTRON INJECTION LAYER FOR AN ORGANIC LIGHT-EMITTING DIODE (OLED) NOVALED GMBH (DE) 2017-06-22 WO disclosed