SCHEMBL19002936

SCHEMBL19002936

PC(c1ccccc1)(c1ccccc1)c1ccc(C(P)(c2ccccc2)c2ccccc2)c(-c2ccccc2C(P)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PLA2G1B P04054 1/20 0.32
NFKB1 P19838 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19002958 0.88 KCNN4 (0.31) ALDH1A1
SCHEMBL1326257 0.88 KCNN4 (0.36) ALDH1A1
SCHEMBL2571569 0.80 ALDH1A1 (0.37) ALDH1A1
SCHEMBL411476 0.78 ALDH1A1 (0.38) ALDH1A1
SCHEMBL1368134 0.76 KCNN4 (0.41) ALDH1A1
Bromide SCHEMBL659623 0.76 ALDH1A1 (0.37) ALDH1A1
SCHEMBL21530763 0.76 KCNN4 (0.31) ALDH1A1
Water SCHEMBL10839715 0.76 ALDH1A1 (0.37) ALDH1A1
Hydrochloric Acid SCHEMBL465147 0.76 ALDH1A1 (0.37) ALDH1A1RAB9A
Iodide SCHEMBL3443160 0.76 ALDH1A1 (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507269-B1 STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT EASTMAN CHEM CO (US) 2020-09-23 EP disclosed
EP-3507269-A1 STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT Eastman Chemical Company (US) 2019-07-10 EP disclosed
WO-2018044827-A1 STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT EASTMAN CHEMICAL COMPANY (US) 2018-03-08 WO disclosed
US-9687837-B1 Stable hydroformylation catalyst for preparation of high N/Iso ratio aldehyde product EASTMAN CHEMICAL COMPANY (US) 2017-06-27 US disclosed