Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.33 |
| ▸ | HDAC4 known ✓ | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28151763 | 0.98 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL411476 | 0.98 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| Iodide SCHEMBL3443160 | 0.96 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL2571569 | 0.96 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| Water SCHEMBL10839715 | 0.96 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| Bromide SCHEMBL659623 | 0.96 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| Phosphine SCHEMBL28051041 | 0.96 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL28235794 | 0.96 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| Ammonia Solution, Strong SCHEMBL28011607 | 0.96 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| Iodide SCHEMBL28849490 | 0.94 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 909 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037814-A | PP adhesive tape suitable for polymer soft package battery and preparation method thereof | 佛山市远创新航新能源材料技术有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-115806569-A | High-temperature-resistant quaternary phosphonium sulfonate organic antibacterial flame-retardant monomer for polyester polymerization, and preparation method and application thereof | 浙江恒逸石化研究院有限公司 | 2023-03-17 | — | — | CN | claimed |
| EP-1347012-B2 | Curable Fluoroelastomers | SOLVAY SPECIALTY POLYMERS IT (IT) | 2020-04-29 | — | — | EP | claimed |
| EP-3212682-B1 | VULCANISABLE COMPOSITIONS COMPRISING ETHYLENE-VINYLACETATE-COPOLYMERS CONTAINING EPOXY GROUPS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2019-01-09 | — | — | EP | claimed |
| US-20170335037-A1 | VULCANIZABLE COMPOSITIONS CONTAINING EPOXY GROUP-CONTAINING ETHYLENE-VINYL ACETATE COPOLYMERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-11-23 | — | — | US | claimed |
| US-9522915-B2 | Method for preparing an important intermediate of linagliptin | 2Y-CHEM, LTD. (CN) | 2016-12-20 | — | — | US | claimed |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | 2Y-CHEM, LTD. (CN) | 2015-10-01 | — | — | US | claimed |
| US-9000058-B2 | Process for devulcanizing vulcanized fluoroelastomers, fluoroelastomers thereof and their use | DOTT. VIOLA & PARTNERS CHEMICAL RESEARCH S.R.L. (IT) | 2015-04-07 | — | — | US | claimed |
| US-20140378562-A1 | Process for devulcanizing vulcanized fluoroelastomers, fluoroelastomers thereof and their use | DOTT. VIOLA & PARTNERS CHEMICAL RESEARCH S.R.L. (IT) | 2014-12-25 | — | — | US | claimed |
| WO-2013132523-A1 | PROCESS FOR DEVULCANIZING VULCANIZED FLUOROELASTOMERS, FLUOROELASTOMERS THEREOF AND THEIR USE | DOTT. VIOLA & PARTNERS CHEMICAL RESEARCH S.R.L. (IT) | 2013-09-12 | — | — | WO | claimed |
| WO-1997044376-A1 | METHOD OF CATALYST DEACTIVATION IN CONTINUOUS POLYETHYLENE TEREPHTHALATE PRODUCTION | WELLMAN, INC. (US) | 1997-11-27 | — | — | WO | claimed |
| US-5658671-A | ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| WO-1997000906-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-01-09 | — | — | WO | claimed |
| US-5451625-A | FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| US-5371143-A | Polymer blend composition of fluorinated elastomers, thermoplastic polymers and thermoplastics elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| US-5319025-A | Curing fluorocarbon elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-07 | — | — | US | claimed |
| EP-0574319-A1 | Fluoroelastomer coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-15 | — | — | EP | claimed |
| US-5008345-A | Two-Part Curing System Containing A Metallic Acid Salt And An Ammonium Or Phosphonium Quaternary Salt | ZEON CHEMICAL USA, INC. (US) | 1991-04-16 | — | — | US | claimed |
| US-4931509-A | EPOXY-CONTAINING MONOMER; EXCELLENT VULCANIZING WITH UREAS, QUATERNARY AMMONIUM AND PHOSPHONIUM SALTS AND POLYCARBOXYLIC ACIDS OR ANHYDRIDES | NIPPON ZEON CO., LTD. (JP) | 1990-06-05 | — | — | US | claimed |
| EP-0309794-A2 | No-post-cure method of curing polyacrylate polymers | Zeon Chemicals USA, Inc. (US) | 1989-04-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | DPP4, DPP9, DPP3 | DPP4 1/4885HDAC4 1177/4885HDAC2 2931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.